Endocrine Abstracts

Introduction: Cellular differentiation and development of germ cells critically depend on a coordinated activation and repression of specific genes. The underlying regulation mechanisms, however, are largely unknown. Here, we describe the interplay between two transcription factors to be critical for cell type-specific expression in testis.Methods: We investigated the binding of CREMτ (cAMP response element modulator tau) and GCNF (germ cell nuclear...